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Cotrimoxazole 480mg Tablet — KATHREX — 480mg | Dr. Med Pharmacy

Prescription MedicinesPrescription required

KATHREX

Cotrimoxazole 480mg Tablet

SKU #: DMP-MD-177

Cotrimoxazole 480mg Tablet is a combination antibacterial medicine containing sulfamethoxazole 400mg and trimethoprim 80mg. It works by blocking two sequential steps in bacterial folate synthesis, helping stop the growth of susceptible bacteria.

FDA Registration Number: DRP-1620

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₱568.00₱398.0030% OFF

VAT incl.

Pack size: 100 Tablets

Prescription required: Prescription medicines require a valid prescription and pharmacist approval before dispensing. Do not use this site to obtain medicines without appropriate medical supervision.

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Product details

Generic Name:Cotrimoxazole

Category:Prescription Medicines

Brand:KATHREX

Strength:480mg

Dosage Form:Tablet

Indications

Used for the treatment of susceptible bacterial infections such as certain urinary tract infections, selected respiratory tract infections, shigellosis, and traveler’s diarrhea. It is also used for the treatment and prevention of Pneumocystis jirovecii pneumonia in appropriate patients.

Contraindications

Hypersensitivity or allergy to sulfamethoxazole, trimethoprim, sulfonamides, or any component of the formulation.
History of drug-induced immune thrombocytopenia caused by trimethoprim or sulfonamides.
Megaloblastic anemia due to folate deficiency.
Marked hepatic impairment.
Severe renal insufficiency when renal function cannot be adequately monitored.
Concomitant use with dofetilide.

Warnings and Precautions

Serious and potentially fatal hypersensitivity and skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis, may occur. Stop treatment immediately and seek medical attention if rash, blistering, mucosal lesions, or other signs of a severe reaction develop.
Use with caution in patients with impaired kidney or liver function, folate deficiency, severe allergies, or bronchial asthma.
Blood disorders, including thrombocytopenia, agranulocytosis, aplastic anemia, and other hematologic abnormalities, may rarely occur.
Hyperkalemia and other electrolyte disturbances may occur, particularly in patients with kidney impairment or those taking medicines that increase potassium levels.
Hemolysis may occur in patients with glucose-6-phosphate dehydrogenase deficiency.
Antibiotic-associated diarrhea and Clostridioides difficile-associated colitis may occur during or after treatment.
Adequate fluid intake should be maintained during treatment unless otherwise directed by a healthcare professional.
Use during pregnancy requires careful medical assessment because trimethoprim interferes with folate metabolism and potential fetal risks have been reported.
Cotrimoxazole should be used only for infections proven or strongly suspected to be caused by susceptible bacteria. Inappropriate antibiotic use may contribute to antimicrobial resistance.
Complete the full prescribed course of treatment unless otherwise instructed by the physician.

Cotrimoxazole 480mg Tablet

Product details

Indications

Contraindications

Warnings and Precautions

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